Details

Autor(en) / Beteiligte

• Stieren, Emily S.
• Sankaran, Deepika
• Lakshminrusimha, Satyan
• Rottkamp, Catherine A.

Titel

Comorbidities and Late Outcomes in Neonatal Pulmonary Hypertension

Ist Teil von

• Clinics in perinatology, 2024-03, Vol.51 (1), p.271-289

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2024

Quelle

MEDLINE

Beschreibungen/Notizen

• Long-term outcomes of persistent pulmonary hypertension of newborn (PPHN) depend on disease severity, duration of ventilation, and associated anomalies. Congenital diaphragmatic hernia survivors may have respiratory morbidities and developmental delay. The presence of PPHN is associated with increased mortality in hypoxic-ischemic encephalopathy, though the effects on neurodevelopment are less clear. Preterm infants can develop pulmonary hypertension (PH) early in the postnatal course or later in the setting of bronchopulmonary dysplasia (BPD). BPD-PH is associated with higher mortality, particularly within the first year. Evidence suggests that both early and late PH in preterm infants are associated with neurodevelopmental impairment.