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The effect of injection of 1:100 000 adrenaline solution in the pterygopalatine fossa on intra-operative bleeding during endoscopic sinonasal surgical procedures in chronic sinusitis: a blinded clinical trial
Ist Teil von
Journal of laryngology and otology, 2024-06, Vol.138 (6), p.638-641
Ort / Verlag
Cambridge, UK: Cambridge University Press
Erscheinungsjahr
2024
Quelle
Alma/SFX Local Collection
Beschreibungen/Notizen
Abstract
Objective
Rhinosinusitis is one of the most common reasons for a visit to otolaryngology clinics. Some patients are candidates for sinus surgery. Infiltration of 1:100 000 adrenaline in the pterygopalatine fossa was studied, with the aim of evaluating the effect on bleeding in the surgical field.
Methods
This double-blind clinical trial was conducted in 2021–2022 on 40 candidates for endoscopic sinus surgery. For each patient, one side of the pterygopalatine fossa was randomly selected to be infiltrated with a vasoconstrictor. Surgical field bleeding on each side was evaluated.
Results
Blood loss was 35.8 ± 20.9 ml in the study group and 38.4 ± 23.7 ml for the control group, with no statistically significant difference between groups (
p
= 0.49). In addition, there was no difference between the two groups in terms of the surgical field based on Boezaart scores.
Conclusion
Although there are some recommendations on the usage of vasoconstrictors via the pterygopalatine foramen, debate remains.