Details

Autor(en) / Beteiligte

• Li, Qing
• Zhu, Zhi-Qiang
• Zhang, Wen-Yi
• Le, Zhang-Gao
• Xie, Zong-Bo

Titel

Visible-light-induced decarboxylative cascade cyclization of acryloylbenzamides with N -hydroxyphthalimide esters via EDA complexes

Ist Teil von

• Organic & biomolecular chemistry, 2024-01, Vol.22 (5), p.965-969

Ort / Verlag

England: Royal Society of Chemistry

Erscheinungsjahr

2024

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A visible-light-induced decarboxylative cascade reaction of acryloylbenzamides with alkyl -hydroxyphthalimide (NHP) esters for the synthesis of various 4-alkyl isoquinolinediones mediated by triphenylphosphine (PPh ) and sodium iodide (NaI) was developed. This operationally simple protocol proceeded the photoactivation of electron donor-acceptor (EDA) complexes between -hydroxyphthalimide esters and NaI/PPh , resulting in multiple carbon-carbon bond formations without the use of precious metal complexes or synthetically elaborate organic dyes, which provided an alternative practical approach to synthesize diverse isoquinoline-1,3(2 ,4 )-dione derivatives.