Details

Autor(en) / Beteiligte

• Yao, Liyuan
• Huang, Xiaobao
• Lin, Tingting
• Qiu, Sheng-Xiang

Titel

Three new anti-inflammatory stilbenoids and a diphenyl ether derivative from Cajanus cajan

Ist Teil von

• Natural product research, 2024-01, p.1-8

Ort / Verlag

England

Erscheinungsjahr

2024

Quelle

Taylor & Francis

Beschreibungen/Notizen

• Three new stilbenoids, namely two rare plant-derived phenanthrenes denominated Cajananthrenes A and B ( , ) and one bibenzyl named Cajanbenzyl ( ), together with a diphenyl ether derivative designated Cajanether ( ), as well as five other known compounds ( - ) were isolated from the ethanolic extract of the leaves of . Their structures were determined through extensive spectroscopic analysis including UV, IR, NMR (1D and 2D) and HRESIMS as well. A plausible biogenesis pathway was proposed for the biosynthesis of compounds - . Compounds and displayed moderate anti-inflammatory activity as evident from the inhibitory effect on NO production in LPS-stimulated RAW 264.7 macrophages with IC values of 73.6 and 44.6 μM respectively.