Details

Autor(en) / Beteiligte

• Saha, Dhiman
• Protich, Zachary
• Wu, Jimmy

Titel

Synthesis of Functionalized Hexahydrocarbazoles by Beckmann Elimination and Nucleophile-Intercepted Beckmann Fragmentation

Ist Teil von

• Organic letters, 2024-01, Vol.26 (1), p.18-21

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2024

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The Beckmann elimination and nucleophile-intercepted Beckmann fragmentation (NuBFr) of oximes starting from regioisomeric indolinyl bicyclic ketones lead to products that are subjected to further synthetic manipulations and ultimately result in the stereospecific formation of densely functionalized hexahydrocarbazoles. The Pd-catalyzed Suzuki–Miyaura cross-coupling reaction of a key alkenyl bromide intermediate with various boronic acids gives arylated products.