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Successful treatment of classic Kaposi sarcoma with Trichophyton rubrum–infected onychomycosis and tinea pedis utilizing combination of oral itraconazole and thalidomide
Ist Teil von
Journal of dermatology, 2024-05, Vol.51 (5), p.727-730
Ort / Verlag
England: Wiley Subscription Services, Inc
Erscheinungsjahr
2024
Quelle
Wiley Online Library - AutoHoldings Journals
Beschreibungen/Notizen
Kaposi sarcoma (KS) is a vascular proliferative tumor caused by human herpesvirus 8. At present, the treatment of KS is difficult and refractory. Here, we report a 68‐year‐old man who was diagnosed with a classical KS with tinea pedis and onychomycosis, infected by Trichophyton rubrum, and treated with itraconazole and thalidomide after locational excision of several bigger nodules. The lesions were relieved during treatment, and recurred after discontinuation. Retreatment still achieved good effect and the therapy was tapered down after control. After the whole course of treatment, the skin lesions subsided significantly without obvious adverse reactions, which showed that itraconazole combined with thalidomide may be another effective and safe treatment for KS in some cases.