Details

Autor(en) / Beteiligte

• Tickner, Anthony
• Aviles, Frank
• Kirsner, Robert
• Lullove, Eric
• Main, Leah
• Suski, Mark
• Wahab, Naz
• Lantis II, John

Titel

Consensus Recommendations for Optimizing the Use of Intact Fish Skin Graft in the Management of Acute and Chronic Lower Extremity Wounds

Ist Teil von

• Wounds (King of Prussia, Pa.), 2023-11, Vol.35 (11), p.e376-e390

Erscheinungsjahr

2023

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Background. Since 2017, the clinical use of IFSG has increased substantially in the United States, with some use in Europe and Asia as well. However, scant consensus data have been published on such use. Objective. The authors sought to develop consensus recommendations for the clinical use of IFSG in the management of acute and chronic LEWs. Methods. A panel of 8 expert clinicians in the United States used a 2-cycle NFG process to develop consensus statements based on their own clinical practice and the literature. At their initial meeting in October 2021, panel members discussed the management of DFUs, VLUs, atypical LEWs, and traumatic LEWs in their practices. Consensus statements were drafted, voted on, and rated by relative importance. At the second meeting in October 2022, the panel discussed the initial survey results; a second survey was conducted, and panel members revised the recommendations and indicated the relative importance of each in the final report. A systematic literature review of English-language articles published from January 2016 through November 2022 was conducted as well, using the search terms: “fish skin,” “piscine graft,” “fish tissue,” “intact fish skin graft,” “Cod skin,” “Omega 3 fatty acid graft.” Results. Forty-three statements were generated and grouped into 5 sections comprising general recommendations for LEWs and recommendations specific to DFUs, VLUs, atypical LEWs, and traumatic LEWs. The primary general recommendation is the need to determine wound etiology based on clinical evaluation and reviewing related test results. For DFUs and VLUs, the main recommendations are to adhere to first-line therapy (ie, standard of care, follow conventional guidelines [multilayer compression therapy], offloading, and assessment of wound perfusion) before introducing IFSG. Conclusions. Publications on and clinical experience in the use of IFSGs have increased substantially in the past several years. The 43 consensus recommendations are meant to guide physicians in the optimal use of IFSG in the management of acute and chronic LEWs.