Details

Autor(en) / Beteiligte

• Kim, Jae Hui
• Choi, Mihyun
• Kim, Seong-Woo
• Park, Kyu Hyung
• Nam, Dong Heun
• Lee, Dae Yeong
• Park, Young-Hoon
• Park, Young-Gun
• Kim, Mirinae
• Lee, Mee Yon
• Choi, Soon-Il
• Kim, Min
• Lee, Junwon
• Moon, Sang Woong
• Chung, Hyewon
• Lee, Young Hoon
• Lee, Min Woo
• Shin, Jae Pil
• Park, Dong Ho
• Park, Han Sang
• Kang, Yong Koo
• Chung, In Young
• Yoo, Woong-Sun
• Cho, Yong-Wun
• Kim, Yu Cheol
• Kang, Kyung Tae
• Jang, Ji Hye
• Choi, Kwang-Eon
• Nam, Ki Tae
• Ahn, So Min
• Lee, Sang Joon
• Lim, Jae Wan
• Ku, Hee Chan
• Yoo, Su Jin
• Choi, Moon Jung
• Lew, Young Ju
• Kim, Joo Yeon
• Lee, Seung Woo
• Bae, Kunho
• Jeong, Woo Jin
• Kwon, Yoon Hyung
• An, Seoung Hyun
• Ahn, Jeeyun
• Shin, Joo Young
• Byon, Ik Soo
• Park, Sung Who
• Kang, Se Woong
• Ham, Don-Il
• Kim, Sang Jin
• Oh, Baek Lok
• Kim, June-Gone
• Lee, Joo Yong
• Lee, Jun Yeop
• Kim, Yoon Jeon
• Chae, Ju Byung
• Kim, Dong Yoon
• Lee, Christopher Seungkyu
• Cho, Kwan Hyuk
• Kim, Min Seok
• Kim, Seong Wook
• Lee, Jung Pil
• Kim, Hoon Dong
• Cho, In Hwan
• Song, Ji Hun
• Lee, Ki Hwang
• Kwon, Han Jo
• Lee, Seung Min
• Lee, Tae Gon
• Han, Jung Il
• Chang, Young Suk
• Min, Jung Kee
• Yang, Yun Sik
• Kim, Soo Han
• Chin, Hee Seung
• Ji, Yong Sok
• Lee, Jong Young
• Kim, Seong Taeck
• Shin, Min Ho
• Kim, Jee Taek
• Han, Yong Seop
• Lee, Woo Hyuk
• Jo, Young Joon
• Kim, Jung Yeul
• Kim, Kyung Tae
• Seo, Eoi Jong
• Lim, Sun Taek
• Lee, Jun Sung
• Kim, Chang Ryong
• Duck-Jin Hwang, Daniel
• Kim, Ha Kyoung
• Ma, Dae Joong
• Hong, In Hwan
• Cho, Bum Joo
• Shin, Yong Un
• Cho, Heeyoon
• Ahn, Seong Joon

Titel

Clinical Factors, Treatment Selection, and Outcomes in Postcataract Fungal Endophthalmitis from Contaminated Viscoelastics

Ist Teil von

• Ophthalmology retina, 2024-05, Vol.8 (5), p.473-480

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2024

Quelle

MEDLINE

Beschreibungen/Notizen

• To investigate the factors associated with treatment outcomes of postcataract surgery fungal endophthalmitis outbreaks related to contaminated viscoelastics. Retrospective analysis of clinical data from multiple institutions. This study included 228 eyes of 210 patients who were diagnosed with postcataract surgery fungal endophthalmitis related to the use of viscoelastic material (Unial, Unimed Pharmaceutical Inc); they were followed up for 6 months after the diagnosis. Clinical features and causative species were identified and treatment outcomes were analyzed in patients who underwent 6 months of follow-up. Propensity score matching was conducted to elucidate the impact of vitrectomy timing and intraocular lens (IOL) removal on treatment outcomes. Clinical factors and selection of treatment modalities associated with treatment outcomes at 6 months. Baseline visual acuity (P < 0.01), age (P = 0.05), and the presence of corneal edema (P < 0.01) were closely associated with poor best-corrected visual acuity (BCVA) at 6 months. Patients who underwent immediate vitrectomy after diagnosis showed significantly better BCVA at 6 months (mean logarithm of minimum angle of resolution 0.26 ± 0.43 vs. 0.52 ± 0.52, P = 0.03) and greater degree of visual improvement (mean −0.17 ± 0.37 improvement vs. 0.10 ± 0.57 deterioration, P = 0.03) than those who underwent deferred vitrectomy. Patients who underwent IOL removal during vitrectomy required a lower number of intravitreal antifungal agent injections (mean 8.9 ± 9.1 vs. 16.7 ± 12.2, P < 0.01) and showed a lower incidence of repeated vitrectomy (20% vs. 82%, P < 0.01) than in those without IOL removal. In postcataract fungal endophthalmitis, prompt vitrectomy at the time of diagnosis resulted in better treatment outcomes, and IOL removal reduced the treatment burden. Prompt and aggressive surgical intervention should be considered for postcataract fungal endophthalmitis. Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.