Details

Autor(en) / Beteiligte

• Berthelsen, Dorthe B
• Simon, Lee S
• Ioannidis, John P A
• Voshaar, Marieke
• Richards, Pam
• Goel, Niti
• Strand, Vibeke
• Nielsen, Sabrina M
• Shea, Beverly J
• Tugwell, Peter
• Bartlett, Susan J
• Hazlewood, Glen S
• March, Lyn
• Singh, Jasvinder A
• Suarez-Almazor, Maria E
• Boers, Maarten
• Stevens, Randall M
• Furst, Daniel E
• Woodworth, Thasia
• Leong, Amye
• Brooks, Peter M
• Flurey, Caroline
• Christensen, Robin

Titel

Stakeholder endorsement advancing the implementation of a patient-reported domain for harms in rheumatology clinical trials: Outcome of the OMERACT Safety Working Group

Ist Teil von

• Seminars in arthritis and rheumatism, 2023-12, Vol.63, p.152288-152288, Article 152288

Ort / Verlag

United States

Erscheinungsjahr

2023

Quelle

ScienceDirect

Beschreibungen/Notizen

• To develop an understanding of the concept of safety/harms experienced by patients involved in clinical trials for their rheumatic and musculoskeletal diseases (RMDs) and to seek input from the OMERACT community before moving forward to developing or selecting an outcome measurement instrument. OMERACT 2023 presented and discussed interview results from 34 patients indicating that up to 171 items might be important for patients' harm-reporting. Domain was defined in detail and supported by qualitative work. Participants in the Special-Interest-Group endorsed (96 %) that enough qualitative data are available to start Delphi survey(s). We present a definition of safety/harms that represents the patient voice (i.e., patients' perception of safety) evaluating the symptomatic treatment-related adverse events for people with RMDs enrolled in clinical trials.