Details

Autor(en) / Beteiligte

• Ushiro, Koji
• Watanabe, Yoshiki
• Kishimoto, Yo
• Kawai, Yoshitaka
• Fujimura, Shintaro
• Asato, Ryo
• Tsujimura, Takashi
• Hori, Ryusuke
• Kumabe, Yohei
• Yasuda, Kaori
• Tamaki, Hisanobu
• Iki, Takehiro
• Kitani, Yoshiharu
• Kurata, Keisuke
• Kojima, Tsuyoshi
• Takata, Kuniaki
• Kada, Shinpei
• Takebayashi, Shinji
• Shinohara, Shogo
• Hamaguchi, Kiyomi
• Miyazaki, Masakazu
• Ikenaga, Tadashi
• Maetani, Toshiki
• Harada, Hiroyuki
• Haji, Tomoyuki
• Omori, Koichi

Titel

Local recurrence and metachronous multiple cancers after transoral nonrobotic surgery for pharyngeal and laryngeal squamous cell carcinoma: A retrospective multicenter study

Ist Teil von

• Head & neck, 2024-01, Vol.46 (1), p.118-128

Ort / Verlag

Hoboken, USA: John Wiley & Sons, Inc

Erscheinungsjahr

2024

Link zum Volltext

Quelle

Wiley Online Library - AutoHoldings Journals

Beschreibungen/Notizen

• Background Late laryngopharyngeal cancers after transoral surgery include not only local recurrences but also metachronous multiple cancers. Methods We compared clinical information, surgical outcomes, and late laryngopharyngeal cancers in patients who underwent transoral nonrobotic surgery for laryngopharyngeal squamous cell carcinoma without lymph node metastases between 2015 and 2021 in a multicenter retrospective study. Results Four hundred and fifty‐seven patients were included. Positive surgical margins were found in 121 patients (26.5%). Twenty‐two patients (4.8%) received additional treatment. Positive horizontal margins of invasive carcinoma (p = 0.003) and positive horizontal margins of carcinoma in situ only (p = 0.032) were independent risk factors for local recurrence, and prior radiotherapy (p = 0.001) for metachronous multiple cancers. Local control was significantly worse without additional treatment (p = 0.049), but there was no significant difference in survival. Conclusions Patients with positive margins had an increased frequency of local recurrence, but salvage therapy was effective.