Details

Autor(en) / Beteiligte

• Yan, Huaipu
• Shan, Jing-Ran
• Zhang, Fengzhi
• Chen, Yuqing
• Zhang, Xinyi
• Liao, Qian
• Hao, Erjun
• Shi, Lei

Titel

Radical Crotylation of Aldehydes with 1,3-Butadiene by Photoredox Cobalt and Titanium Dual Catalysis

Ist Teil von

• Organic letters, 2023-10, Vol.25 (42), p.7694-7699

Ort / Verlag

American Chemical Society

Erscheinungsjahr

2023

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Metal-hydride hydrogen atom transfer (MHAT) has been recognized as a powerful method for alkene functionalization; however, photochemical MAT-mediated chemoselective functionalization of dienes remains undeveloped. In this study, we report a radical strategy (1e–) through MHAT using photoredox cobalt and titanium dual catalysis for aldehyde crotylation with butadiene, achieving excellent regio- and diastereoselectivity.