The New England journal of medicine, 2023-10, Vol.389 (15), p.1357-1367
- Donovan, Joseph
- Bang, Nguyen D.
- Imran, Darma
- Nghia, Ho D.T.
- Burhan, Erlina
- Huong, Dau T.T.
- Hiep, Nguyen T.T.
- Ngoc, Lam H.B.
- Thanh, Dang V.
- Thanh, Nguyen T.
- Wardhani, Anna L.S.
- Maharani, Kartika
- Gasmara, Cakra P.
- Hanh, Nguyen H.H.
- Oanh, Pham K.N.
- Estiasari, Riwanti
- Thu, Do D.A.
- Kusumaningrum, Ardiana
- Dung, Le T.
- Giang, Do C.
- Ha, Dang T.M.
- Lan, Nguyen H.
- Chau, Nguyen V.V.
- Nguyet, Nguyen T.M.
- Geskus, Ronald B.
- Thuong, Nguyen T.T.
- Kestelyn, Evelyne
- Hamers, Raph L.
- Phu, Nguyen H.
- Thwaites, Guy E.
2023
Details
- Autor(en) / Beteiligte
- Donovan, Joseph
- Bang, Nguyen D.
- Imran, Darma
- Nghia, Ho D.T.
- Burhan, Erlina
- Huong, Dau T.T.
- Hiep, Nguyen T.T.
- Ngoc, Lam H.B.
- Thanh, Dang V.
- Thanh, Nguyen T.
- Wardhani, Anna L.S.
- Maharani, Kartika
- Gasmara, Cakra P.
- Hanh, Nguyen H.H.
- Oanh, Pham K.N.
- Estiasari, Riwanti
- Thu, Do D.A.
- Kusumaningrum, Ardiana
- Dung, Le T.
- Giang, Do C.
- Ha, Dang T.M.
- Lan, Nguyen H.
- Chau, Nguyen V.V.
- Nguyet, Nguyen T.M.
- Geskus, Ronald B.
- Thuong, Nguyen T.T.
- Kestelyn, Evelyne
- Hamers, Raph L.
- Phu, Nguyen H.
- Thwaites, Guy E.
- Titel
- Adjunctive Dexamethasone for Tuberculous Meningitis in HIV-Positive Adults
- Ist Teil von
- The New England journal of medicine, 2023-10, Vol.389 (15), p.1357-1367
- Ort / Verlag
- United States: Massachusetts Medical Society
- Erscheinungsjahr
- 2023
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- In this randomized trial, HIV-positive adults with tuberculous meningitis were assigned to receive 6 to 8 weeks of dexamethasone or placebo in addition to tuberculosis treatment. No benefit of dexamethasone was observed.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793eISSN: 1533-4406DOI: 10.1056/NEJMoa2216218Titel-ID: cdi_proquest_miscellaneous_2876635855
- Format
- –
- Schlagworte
- Adult, AIDS, Allergy, Anti-Retroviral Agents - adverse effects, Anti-Retroviral Agents - therapeutic use, Antiretroviral therapy, Antitubercular Agents - adverse effects, Antitubercular Agents - therapeutic use, CD4 antigen, Chemotherapy, Dexamethasone, Dexamethasone - adverse effects, Dexamethasone - therapeutic use, Disease, Double-Blind Method, Drug Therapy, Combination - adverse effects, Encephalitis, Enrollments, Glasgow Coma Scale, Global Health, Glucocorticoids - adverse effects, Glucocorticoids - therapeutic use, HIV, HIV Infections - complications, HIV Infections - drug therapy, HIV Seropositivity - complications, HIV Seropositivity - drug therapy, Hospitals, Human immunodeficiency virus, Humans, Immune reconstitution, Immune system, Immunology, Infectious Disease, Infectious Disease General, Inflammation, Inflammatory Disease, Investigations, Meningitis, Mortality, Neurology, Neurosurgery, Oral administration, Placebos, Statistical analysis, Tuberculosis, Tuberculosis, Meningeal - complications, Tuberculosis, Meningeal - drug therapy