Details

Autor(en) / Beteiligte

• Cui, Jing
• Du, Xin
• He, Liu
• Xia, Shi‐Jun
• Tang, Ri‐Bo
• Sang, Cai‐Hua
• Long, De‐Yong
• Dong, Jian‐Zeng
• Ma, Chang‐Sheng

Titel

Impact of pre‐ablation left appendage flow velocities on long term recurrence of catheter ablation for paroxysmal atrial fibrillation

Ist Teil von

• Pacing and clinical electrophysiology, 2023-11, Vol.46 (11), p.1412-1418

Ort / Verlag

Hoboken: Wiley Subscription Services, Inc

Erscheinungsjahr

2023

Link zum Volltext

Quelle

Wiley Online Library - AutoHoldings Journals

Beschreibungen/Notizen

• Background Despite undergoing a single ablation, many patients with paroxysmal atrial fibrillation (PAF) experience a gradually increasing recurrence rate. This study aims to examine the relationship between left atrial appendage emptying velocity (LAAeV) and filling velocity (LAAfV) profiles and 3‐year recurrence of AF after ablation. Methods We conducted a prospective study of 658 consecutive PAF patients who underwent their first ablation between January 2018 and December 2019. We collected the clinical and echocardiographic characteristics of the patients. LAAeV and LAAfV were obtained from a transesophageal echocardiogram (TEE) before catheter ablation. Patients were followed at regular intervals to monitor for the primary outcome of AF recurrence. Results After a median follow‐up period of 35.3 months (range, 10.7–36.3), 288 patients (43.8%) experienced AF recurrence after catheter ablation. Patients who experienced AF recurrence had decreased LAAeV and LAAfV (LAAeV: 56.5 ± 21.2 vs. 59.6 ± 20.7 cm/s, p = .052; LAAfV: 47.5 ± 17.9 vs. 51.7 ± 18.2, p = .003). Kaplan–Meier analysis showed that patients in the low LAAeV (<55 cm/s) group had a poorer event‐free survival rate than those in the high LAAeV (≥55 cm/s) group (log‐rank p = .012). Patients with LAAfV <48 cm/s had a significantly higher risk of AF recurrence than those with LAAfV ≥48 cm/s (log‐rank p = .003). In the multivariable model, low LAAfV pre‐ablation in TEE‐guided was significantly independently associated with 3‐year recurrence after single radiofrequency ablation in patients with PAF, along with LA dimension and duration of AF. Conclusion This study found an independent association between low LAAfV pre‐ablation in TEE‐guided and 3‐year recurrence after single radiofrequency ablation in patients with PAF.