Details

Autor(en) / Beteiligte

• He, Shengduo
• Jiang, Hong
• Tian, Yu
• Zhang, Wei
• Teng, Guigen
• Wang, Huahong

Titel

Ulcerative colitis overall disease severity index predicts colectomy: a prospective cohort study

Ist Teil von

• Revista española de enfermedades digestivas, 2024-02, Vol.116 (2), p.77-82

Ort / Verlag

Spain: Sociedad Espanola de Patologia Digestivas

Erscheinungsjahr

2024

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• ulcerative colitis (UC) overall disease severity index (DSI) has been established. A prospective cohort study was performed to find the value of DSI to predict colectomy within one and four years and explored the association between DSI and other indexes. the hospitalized UC patients were enrolled from March 2018 to January 2019 in this single center study. DSI, Truelove and Witts criteria, Mayo index and Seo index were assessed by medical records. Outcome was whether to undergo colectomy within one and four years and was obtained by telephone survey or medical records. Index values of predicting colectomy within one and four years were evaluated using receiver operating characteristics (ROC) curves. one hundred and thirty-eight of 233 hospitalized UC patients were enrolled. Within one year, the follow-up period was less than one year for six patients and two patients had died. A further nine patients underwent colectomy. The Spearman correlation coefficient between DSI and Truelove and Witts criteria, Mayo index and Seo index were 0.730, 0.839 and 0.843, respectively. Using these indices to predict colectomy within one and four years, the area under the curve of DSI was more than those of other indices and the cut-off value of DSI was 79. a good correlation of DSI with other indexes was demonstrated. DSI can be used to predict the need for colectomy within one or four years.