Details

Autor(en) / Beteiligte

• Hazra, Arijit
• Ghosh, Asit
• Yadav, Neeraj
• Banerjee, Prabal

Titel

Organocatalytic (3+3)-cycloaddition of ortho -substituted phenyl nitrones with aryl cyclopropane carbaldehydes: a facile access to enantioenriched 1,2-oxazinanes

Ist Teil von

• Chemical communications (Cambridge, England), 2023-09, Vol.59 (74), p.11133-11136

Ort / Verlag

Cambridge: Royal Society of Chemistry

Erscheinungsjahr

2023

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The first asymmetric (3+3)-cycloaddition of ortho -substituted phenyl nitrones with aryl cyclopropane carbaldehydes has been demonstrated by secondary amine catalysts. While the other ortho -substituents gave 1,2-oxazinanes, ortho -hydroxy ones provided a novel class of tetrahydrochromeno-1,2-oxazine cores via rare 1,3-aryl migration, followed by cyclization. An unusual type of asymmetric approach was also recognized.