Details

Autor(en) / Beteiligte

• Xu, Huiwei
• Zheng, Wanyao
• Liu, Wen-Deng
• Zhou, Yuqiao
• Lin, Luqing
• Zhao, Jiannan

Titel

Silylacylation of Alkenes through N‑Heterocyclic Carbene Catalysis

Ist Teil von

• Organic letters, 2023-08, Vol.25 (30), p.5579-5584

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2023

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The construction of silicon-containing molecules has received increasing attention in recent years. Herein, we report the generation of silyl radicals through NHC catalysis under mild reaction conditions. This methodology offers a novel and convenient route to a diverse range of β-silyl ketones with a broad substrate scope and good functional group compatibility. Both the radical clock and electrochemical studies are consistent with the hypothesis of ground-state SET, and a plausible mechanism for the organocatalytic transformation is proposed.