Details

Autor(en) / Beteiligte

• Viadanna, Pedro H. O.
• Grace, Savannah G.
• Logan, Tracey D.
• DeRuyter, Emily
• Loeb, Julia C.
• Wilson, Kristen N.
• White, Zoe S.
• Krauer, Juan M. C.
• Lednicky, John A.
• Waltzek, Thomas B.
• Wisely, Samantha M.
• Subramaniam, Kuttichantran

Titel

Characterization of two novel reassortant bluetongue virus serotype 1 strains isolated from farmed white-tailed deer (Odocoileus virginianus) in Florida, USA

Ist Teil von

• Virus genes, 2023-10, Vol.59 (5), p.732-740

Ort / Verlag

New York: Springer US

Erscheinungsjahr

2023

Quelle

springer (창간호~2014)

Beschreibungen/Notizen

• Hemorrhagic diseases caused by epizootic hemorrhagic disease virus or by bluetongue virus (BTV) are the most important orbivirus diseases affecting ruminants, including white-tailed deer (WTD). Bluetongue virus is of particular concern for farmed WTD in Florida, given its lethality and its wide distribution throughout the state. This study reports the clinical findings, ancillary diagnostics, and genomic characterization of two BTV serotype 1 strains isolated from two farmed WTD, from two different farms in Florida in 2019 and 2022. Phylogenetic and genetic analyses indicated that these two novel BTV-1 strains were reassortants. In addition, our analyses reveal that most genome segments of these strains were acquired from BTVs previously detected in ruminants in Florida, substantiating their endemism in the Southeastern U.S. Our findings underscore the need for additional research to determine the genetic diversity of BTV strains in Florida, their prevalence, and the potential risk of new BTV strains to WTD and other ruminants.