Details

Autor(en) / Beteiligte

• Ligia, Silvio
• Morano, Salvatore Giacomo
• Kaiser, Francesca
• Micozzi, Alessandra
• Chistolini, Antonio
• Barberi, Walter
• Arena, Valentina
• Piciocchi, Alfonso
• Forgione, Maurizio
• Gasperini, Giulia
• Berneschi, Paola
• Testi, Anna Maria

Titel

Peripherally inserted central venous catheter for pediatric acute leukemia: A retrospective 11-year single-center experience

Ist Teil von

• The journal of vascular access, 2023-07, p.11297298231185222-11297298231185222

Ort / Verlag

United States

Erscheinungsjahr

2023

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Peripherally inserted central catheters (PICCs) are successfully increasingly used in children in onco-hematologic setting. PICC insertion, especially in oncologic patients, can be associated with adverse events (thrombosis, mechanical complications, and infections). Data regarding the use of PICC, as long-term access in pediatric patients with severe hematologic diseases, are still limited. We retrospectively evaluated the safety and efficacy of 196 PICC, inserted in 129 pediatric patients with acute leukemia diagnosed and treated at Pediatric Hematology Unit, Sapienza University of Rome. The 196 PICC analyzed were in situ for a median dwell time of 190 days (range 12-898). In 42 children, PICC was inserted twice and in 10, three times or more due to hematopoietic stem cell transplant, disease recurrence, or PICC-related complications. The overall complication rate was 34%: catheter-related bloodstream infections (CRBSI) occurred in 22% of cases after a median time of 97 days; a catheter-related thrombosis (CRT) in 3.5% and mechanical complications in 9% of cases. Premature removal for complications occurred in 30% of PICC. One death from CRBSI was observed. To our knowledge, this study represents the largest cohort of pediatric patients who have inserted the PICC for acute leukemia. In our experience, PICC was a cheap, safe, and reliable device for long-term intravenous access in children with acute leukemia. This has been possible with the help of dedicated PICC team.