Details

Autor(en) / Beteiligte

• Silva, Tatiana Schnorr
• Horvath, Jaqueline Driemeyer Correia
• Pereira, Mariana Pinto
• David, Caroline Nespolo de
• Vargas, Dora Fraga
• Rigoni, Lisandra Della Costa
• Sartor, Ivaine Tais Sauthier
• Kern, Luciane Beatriz
• da Silva, Priscila de Oliveira
• Paz, Alessandra Aparecida
• Daudt, Liane Esteves
• Astigarraga, Claudia Caceres

Titel

Impact of waitlist time on post-HSCT survival: a cohort study at a hospital in southern Brazil

Ist Teil von

• Hematology, Transfusion and Cell Therapy, 2023-05

Ort / Verlag

Brazil: Elsevier España, S.L.U

Erscheinungsjahr

2023

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The time elapsed from diagnosis to hematopoietic stem cell transplantation (HSCT) is influenced by numerous factors. In Brazil, patients using the public health system are also dependent on the availability of HSCT-specific beds in the hematology ward. We conducted a cohort study of listed patients who underwent allogeneic HSCT at a Brazilian public hospital to investigate the impact of the waitlist time on post-HSCT survival. The median time from diagnosis to HSCT was 19 months (IQR, 10 - 43), of which 6 months (IQR, 3 - 9) were spent on the waitlist. The time on the waitlist for HSCT appeared to influence mainly the survival of adult patients (≥ 18 years), with an increasing risk according to this time (RR, 3.53 and 95%CI, 1.81 - 6.88 for > 3 and ≤ 6 months; RR 5.86 and 95%CI, 3.26 - 10.53 for > 6 and ≤ 12 months, and; RR 4.24 and 95%CI, 2.32 - 7.75 for > 12 months). Patients who remained on the waitlist for less than 3 months had the highest survival (median survival, 856 days; IQR, 131 - 1607). The risk of reduced survival was about 6-fold higher (95%CI, 2.8 - 11.5) in patients with malignancies.