Details

Autor(en) / Beteiligte

• Lee, Dain
• Kim, Kyung-Hee
• Park, Jong-Won
• Lee, Ju-Hyeong
• Kim, Jun-Hwan

Titel

High water temperature-mediated immune gene expression of olive flounder, Paralichthys olivaceus according to pre-stimulation at high temperatures

Ist Teil von

• Environmental toxicology and pharmacology, 2023-08, Vol.101, p.104159-104159, Article 104159

Ort / Verlag

Netherlands: Elsevier B.V

Erscheinungsjahr

2023

Quelle

MEDLINE

Beschreibungen/Notizen

• Increased ocean temperature due to global warming affects the health and immunity of fish. In this study, juvenile Paralichthys olivaceus were exposed to high temperature after pre-heat (Acute: Acute heat shock at 32 °C, AH-S: Acquired heat shock at 28 °C & short recovery (2 h) and heat shock at 32 °C, AH-L: acquired heat shock at 28 °C and long recovery (2 days), AH-LS: acquired heat shock at 28 °C & long (2 days) + short (2 h) recovery). Heat shock after pre-heat significantly upregulated various immune-related genes, including interleukin 8 (IL-8), c-type lysozyme (c-lys), immunoglobulin M (IgM), Toll-like receptor 3 (tlr3), major histocompatibility complex IIα (mhcIIα) and cluster of differentiation 8α (cd8α) in the liver and brain of P. olivaceus. This study showed pre-exposure to high temperatures below the critical temperature can activate fish immunity and increase tolerance to high temperatures. [Display omitted] •The effect of water temperature stimulation prior to high water temperature was confirmed.•The IL-8 and lysozyme genes of P. olivaceus were significantly upregulated in the AH-L and AH-LS.•The Ig M, TLR3 and MHCIIa were significantly upregulated in the AH-S, AH-L and AH-SL groups.•The CD8α gene expression was also significantly increased in the AH-L and AH-SL.•Pre-exposure to high water temperature activated the immunity of P. olivaceus.