Details

Autor(en) / Beteiligte

• Chen, Xiao-Hui
• Cui, Hai-Lei

Titel

AcBr/DMSO Mediated Sulfenylation of Pyrrolo[2,1‑a]isoquinolines

Ist Teil von

• Journal of organic chemistry, 2023-06, Vol.88 (11), p.7347-7361

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2023

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• We have developed a mild sulfenylation of pyrrolo­[2,1-a]­isoquinolines with acetyl bromide and dimethyl sulfoxide. A wide range of functionalized pyrrolo­[2,1-a]­isoquinolines could be prepared efficiently through the formation of a C–S bond with thiophenols (27 examples, 36–94% yields). The current strategy can also be utilized for functionalization of pyrrolo­[1,2-a]­quinolines and indole.