Details

Autor(en) / Beteiligte

• Falletto, E.
• Martellucci, J.
• Rossitti, P.
• Bondurri, A.
• Zaffaroni, G.
• Ascanelli, S.
• Chimisso, L.
• Lauretta, A.
• Mirafiori, M.
• Clementi, I.
• Ripetti, V.
• Lufarelli, P.
• Cestaro, G.
• Bottini, C.
• Bellini, M.
• Lambiase, C.
• Di Candido, F.
• Zattoni, D.
• Cornaglia, S.
• Tonello, P.
• Zucchi, E.

Titel

Transanal irrigation in functional bowel disorders and LARS: short-term results from an Italian national study

Ist Teil von

• Techniques in coloproctology, 2023-06, Vol.27 (6), p.481-490

Ort / Verlag

Cham: Springer International Publishing

Erscheinungsjahr

2023

Quelle

SpringerLink

Beschreibungen/Notizen

• Purpose To evaluate the potential benefits associated with the short-term (6 months) treatment with transanal irrigation (TAI) in patients suffering from functional constipation (FC), functional fecal incontinence (FI), and low anterior resection syndrome (LARS). Methods A multicenter observational study (12 centers; 369 patients) was conducted to assess the following primary and secondary objectives: to evaluate the level of satisfaction regarding bowel control and quality of life (QoL); to evaluate bowel symptoms severity and dropout frequency and reason. To this aim, validated questionnaires were provided to the patients at baseline (T0) and after 6 months of TAI treatment (T6) performed with the medical device Peristeen ® Plus (Coloplast A/S, Denmark). Statistical analyses were conducted to compare the outcomes obtained at T0 and T6. Results A 6-month treatment with TAI enabled a statistically significant ( p  < 0.05) improvement of QoL scores, satisfaction scores regarding bowel control, and severity indexes of disorder-related symptoms in patients suffering from FC, FI, and LARS. Globally, 8.0% of patients discontinued the treatment after 6 months as a result of occurrence of symptoms (2.4%) or other justifications (3.8%) such as personal reasons. None of the dropouts were due to treatment inefficacy. Conclusion Results of the present study suggest that short-term TAI treatment is beneficial for patients suffering from functional bowel disorders and LARS. Future analysis of prospective data will focus on the clinical outcomes associated with the long-term use (up to 24 months) of TAI when dealing with these types of medical conditions.