Details

Autor(en) / Beteiligte

• Ai, H.
• Flask, C.
• Weinberg, B.
• Shuai, X.-T.
• Pagel, M. D.
• Farrell, D.
• Duerk, J.
• Gao, J.

Titel

Magnetite-Loaded Polymeric Micelles as Ultrasensitive Magnetic-Resonance Probes

Ist Teil von

• Advanced materials (Weinheim), 2005-08, Vol.17 (16), p.1949-1952

Ort / Verlag

Weinheim: WILEY-VCH Verlag

Erscheinungsjahr

2005

Quelle

Wiley Online Library All Journals

Beschreibungen/Notizen

• Increased contrast in magnetic resonance imaging (MRI) is accomplished using polymeric micelles loaded with superparamagnetic iron oxide (SPIO) nanoparticles encapsulated in biocompatible, biodegradable poly(ϵ‐caprolactone)‐b‐poly(ethylene glycol) (PCL‐b‐PEG) copolymers (see Figure). The loaded micelles show significantly improved T2 relaxivities and remarkable MRI detection sensitivity.