Details

Autor(en) / Beteiligte

• Seidler, Anna Lene
• Hunter, Kylie E
• Barba, Angie
• Aberoumand, Mason
• Libesman, Sol
• Williams, Jonathan G
• Shrestha, Nipun
• Aagerup, Jannik
• Gyte, Gill
• Montgomery, Alan
• Duley, Lelia
• Askie, Lisa

Titel

Optimizing cord management for each preterm baby – Challenges of collating individual participant data and recommendations for future collaborative research

Ist Teil von

• Seminars in perinatology, 2023-06, Vol.47 (4), p.151740-151740, Article 151740

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2023

Quelle

MEDLINE

Beschreibungen/Notizen

• The optimal cord management strategy at birth for each preterm baby is still unknown, despite more than 100 randomized controlled trials (RCTs) undertaken on this question. To address this, we brought together all RCTs examining cord management strategies at preterm birth in the iCOMP (individual participant data on COrd Management at Preterm birth) Collaboration, to perform an individual participant data network meta-analysis. In this paper, we describe the trials and tribulations around obtaining individual participant data to resolve controversies around cord clamping, and we derive key recommendations for future collaborative research in perinatology. To reliably answer outstanding questions, future cord management research needs to be collaborative and coordinated, by aligning core protocol elements, ensuring quality and reporting standards are met, and carefully considering and reporting on vulnerable sub-populations. The iCOMP Collaboration is an example of the power of collaboration to address priority research questions, and ultimately improve neonatal outcomes worldwide.