Details

Autor(en) / Beteiligte

• Sorabad, Ganesh Shivayogappa
• Yang, Ding-Yah

Titel

(4 + 3) Cycloaddition Reaction of Sulfonylphthalide with N,N′‑Cyclic Azomethine Imines: Synthesis of Pyrimidinone-Fused Naphthoquinones

Ist Teil von

• Organic letters, 2023-04, Vol.25 (14), p.2515-2519

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2023

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A base-mediated [4 + 3] cycloaddition reaction of sulfonylphthalide with N,N′-cyclic azomethine imines to facilely synthesize novel pyrimidinone-fused naphthoquinones is described. The prepared compounds can be readily converted to isoquinoline-1,4-dione derivatives via alkaline methanolysis. Alternatively, the isoquinoline-1,4-dione can also be prepared by base-mediated one-pot three-component reaction of sulfonylphthalide with N,N′-cyclic azomethine imines in methanol.