Details

Autor(en) / Beteiligte

• Zhou, Ziyi
• Ma, Wencheng
• Li, Feiyu
• Zhong, Dan
• Zhang, Wenxuan
• Liu, Luming
• Zhang, Jingna
• Zhu, Yisong
• Su, Peng

Titel

Deciphering the distribution and microbial secretors of extracellular polymeric substances associated antibiotic resistance genes in tube wall biofilm

Ist Teil von

• The Science of the total environment, 2023-07, Vol.881, p.163218-163218, Article 163218

Ort / Verlag

Netherlands: Elsevier B.V

Erscheinungsjahr

2023

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Antibiotics and disinfectants have both been proposed to exert selective pressures on the biofilm as well as affecting the emergence and spread of antibiotic resistance genes (ARGs). However, the transfer mechanism of ARGs in drinking water distribution system (DWDS) under the coupling effect of antibiotics and disinfectants has not been completely understood. In the current study, four lab-scale biological annular reactors (BARs) were constructed to evaluate the effects of sulfamethoxazole (SMX) and NaClO coupling in DWDS and reveal the related mechanisms of ARGs proliferation. TetM was abundant in both the liquid phase and the biofilm, and redundancy analysis showed that the total organic carbon (TOC) and temperature were significantly correlated with ARGs in the water phase. There was a significant correlation between the relative abundance of ARGs in the biofilm phase and extracellular polymeric substances (EPS). Additionally, the proliferation and spread of ARGs in water phase were related to microbial community structure. Partial least-squares path modeling showed that antibiotic concentration may influence ARGs by affecting MGEs. These findings help us to better understand the diffusion process of ARGs in drinking water and provide a theoretical support for technologies to control ARGs at the front of pipeline. [Display omitted] •Residual antibiotics coupled disinfectants will affect microbial resistance in DWDS.•It is the first time to simulate tube wall lining shedding in a reactor.•Pipe materials have different effects on the spread of resistome in biofilm.