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Abstract
Days of therapy (DOT) currently serve as the standard antimicrobial utilization metric. However, by assigning the same weight to each agent rather than accounting for differences in spectrum of activity, DOT ignore key differences between agents that are fundamental to infectious diseases and critical to antimicrobial stewardship. Spectrum scoring assigns numeric values to individual antibiotic agents to quantify their spectrum of activity, allowing for the normalization of antibiotic utilization data. When used in conjunction with traditional metrics, spectrum scores may offer further clarity to antibiotic utilization; however, issues related to development, application, and standardization of spectrum scores remain. Despite these challenges, the potential applications of spectrum scores are vast. Here, we summarize existing data and explore the future of spectrum scoring, including application to both data analysis and routine patient care, use in inpatient and outpatient settings, integration within the electronic medical record, and opportunities for future research.
Spectrum scores assign numeric values to individual antibiotic agents to quantify their spectrum of activity; however, issues related to the development, application, and standardization of spectrum scores remain. Despite these challenges, the potential future applications of spectrum scores are vast.
Sprache
Englisch
Identifikatoren
ISSN: 1058-4838
eISSN: 1537-6591
DOI: 10.1093/cid/ciad189
Titel-ID: cdi_proquest_miscellaneous_2793991308
Format
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