Details

Autor(en) / Beteiligte

• Su‐Velez, Brooke M.
• Hartman, Gary E.
• Seeley, Hilary
• Orloff, Lisa A.
• Noel, Julia E.
• Meister, Kara D.

Titel

Parathyroid Autofluorescence in Pediatric Thyroid Surgery: Experience With False Positive and False Negative Results

Ist Teil von

• Otolaryngology-head and neck surgery, 2023-07, Vol.169 (1), p.185-189

Ort / Verlag

England

Erscheinungsjahr

2023

Quelle

Wiley Online Library

Beschreibungen/Notizen

• Devices for near‐infrared light stimulation of autofluorescence (NIRAF) allow for intraoperative identification of parathyroid glands with high sensitivity in adults. However, their performance in the pediatric population is unknown. In this case series with chart review at a tertiary academic children's hospital, we investigated pediatric patients undergoing thyroid surgery and concurrent use of a probe‐based NIRAF device. Thirteen patients (ages 6‐18 years) underwent thyroid and/or neck dissection procedures, and 2 patients had revision procedures for a total of 15 cases with the NIRAF device. Eight cases had NIRAF values that matched surgeon opinion of parathyroid tissue or histology when available. Six cases had false positive NIRAF readings (40.0%) and 1 case had false negative readings (6.7%). Compared with surgeon opinion or histology, the NIRAF device confirmed 26 of 34 parathyroid gland candidates (76.5%). These devices need further investigation in pediatric patients, whose tissues may have different autofluorescence characteristics.