Bulletin of experimental biology and medicine, 2023-02, Vol.174 (4), p.451-454
2023
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Details
- Autor(en) / Beteiligte
- Titel
- Effect of Changes in the Redox Status on Biofilm Formation in Escherichia coli
- Ist Teil von
- Bulletin of experimental biology and medicine, 2023-02, Vol.174 (4), p.451-454
- Ort / Verlag
- New York: Springer US
- Erscheinungsjahr
- 2023
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Changes in the redox balance in the medium and in Escherichia coli cells significantly affect the ability of bacteria to form biofilms. An increase in the level of aeration in the culture of wild-type bacteria led to a 3-fold decrease in the mass of biofilms. Mutants lacking components of the glutathione and thioredoxin redox systems, as well as transporters involved in the transmembrane cycling of glutathione, demonstrated increased biofilm formation ability. The effect of exogenous glutathione on biofilm formation depended on the culturing conditions. The addition of 0.1-1 mM Trolox (a water-soluble analog of vitamin E) was accompanied by a 30-40% reduction in biofilm formation.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0007-4888eISSN: 1573-8221DOI: 10.1007/s10517-023-05727-zTitel-ID: cdi_proquest_miscellaneous_2786104769
- Format
- –
- Schlagworte
- Aeration, Bacteria, Biofilms, Biomedical and Life Sciences, Biomedicine, Cell Biology, Cell culture, E coli, Escherichia coli, Escherichia coli - genetics, Escherichia coli - metabolism, Escherichia coli Proteins - genetics, Escherichia coli Proteins - metabolism, Escherichia coli Proteins - pharmacology, Glutathione, Immunology, Internal Medicine, Kinases, Laboratory Medicine, Microorganisms, Oxidation-Reduction, Pathology, Proteins, Thioredoxin, Vitamin E