Details

Autor(en) / Beteiligte

• Quigley, Suzanne
• Asad, Murva
• Doherty, Colin
• Byrne, Danielle
• Cronin, Simon
• Kearney, Hugh

Titel

Concurrent diagnoses of Tuberous sclerosis and multiple sclerosis

Ist Teil von

• Multiple sclerosis and related disorders, 2023-03, Vol.71, p.104586-104586, Article 104586

Ort / Verlag

Netherlands: Elsevier B.V

Erscheinungsjahr

2023

Quelle

MEDLINE

Beschreibungen/Notizen

• Tuberous sclerosis (TS) is a monogenic disorder which causes disabling neurological symptoms. Similarly, multiple sclerosis (MS) may result in disability, but in contrast, is diagnosed without genetic testing. Clinicians are advised to exercise caution in diagnosing MS in the presence of a pre-existing genetic disorder, as it may be a potential ‘red flag’. A dual diagnosis of MS and TS has not previously been reported in the literature. We provide two cases of known cases of TS who presented with new neurological symptoms and associated physical signs compatible with a dual diagnosis of TS/MS.