Details

Autor(en) / Beteiligte

• Cui, Hai-Lei

Titel

Bromination of Pyrrolo[2,1‑a]isoquinolines with Acetyl Bromide and Dimethyl Sulfoxide

Ist Teil von

• Journal of organic chemistry, 2023-03, Vol.88 (5), p.2822-2831

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2023

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A mild bromination of pyrrolo­[2,1-a]­isoquinolines has been achieved using acetyl bromide and dimethyl sulfoxide. A series of brominated pyrrolo­[2,1-a]­isoquinolines could be obtained in moderate to excellent yields (46–99%) at room temperature. This strategy can also be expanded to the facile bromination of polysubstituted pyrroles, indoles, electron-rich phenols, aniline, and 2-naphthol.