Details

Autor(en) / Beteiligte

• Gola, Ajay Kant
• Sharma, Ajay
• Pandey, Satyendra Kumar

Titel

Synthesis of α‑Carbonyl-α′-amide Sulfoxonium Ylides from Isocyanates with Complete Atom Economy

Ist Teil von

• Organic letters, 2023-02, Vol.25 (7), p.1214-1217

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2023

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• An efficient catalyst- and additive-free facile synthesis of α-carbonyl-α′-amide sulfoxonium ylides from isocyanates and β-ketosulfoxonium ylides with complete atom economy has been described. The β-ketosulfoxonium ylides and isocyanates adorned with various functional groups were well-tolerated and afforded moderate to high yields of the α-carbonyl-α′-amide sulfoxonium ylide derivatives. Finally, using large-scale reactions and converting the synthesized ylides into other valuable compounds, we demonstrated the practicality of this synthetic method.