Details

Autor(en) / Beteiligte

• Evaniew, Nathan
• Coyle, Matthew
• Rampersaud, Y Raja
• Bailey, Christopher S
• Jacobs, W Bradley
• Cadotte, David W
• Thomas, Kenneth C
• Attabib, Najmedden
• Paquet, Jérôme
• Nataraj, Andrew
• Christie, Sean D
• Weber, Michael H
• Phan, Philippe
• Charest-Morin, Raphaële
• Fisher, Charles G
• Hall, Hamilton
• McIntosh, Greg
• Dea, Nicolas

Titel

Timing of Recovery After Surgery for Patients With Degenerative Cervical Myelopathy: An Observational Study From the Canadian Spine Outcomes and Research Network

Ist Teil von

• Neurosurgery, 2023-02, Vol.92 (2), p.271-282

Ort / Verlag

United States

Erscheinungsjahr

2023

Quelle

Oxford Journals 2020 Medicine

Beschreibungen/Notizen

• The time course over which postoperative neurological recovery occurs after surgery for degenerative cervical myelopathy occurs is poorly understood. To determine the time point at which patients experience significant neurological improvement. We reviewed data from an ongoing prospective multicenter cohort study. We measured neurological function at 3 months, 1 year, and 2 years after surgery using the modified Japanese Orthopedic Association (mJOA) scale. We implemented minimal clinical important differences (MCIDs) to guide interpretation of mJOA scores, and we used 1-way analysis of variance to compare changes between follow-up intervals. Among 330 patients, the mean overall mJOA improved from 12.9 (SD 2.6) to 14.6 (SD 2.4) at 3 months, 14.7 (SD 2.4) at 1 year, and 14.8 (SD 2.5) at 2 years. The difference in means was statistically significant (P < .01) at the interval from baseline to 3 months postoperatively, but not from 3 months to 1 year or 1 year to 2 years. The MCID was reached by 161 patients at 3 months, 32 more at 1 year, and 15 more at 2 years, with a statistically significant difference only at 3 months. Patients with moderate or severe disease reached the MCID more frequently than those with mild disease. Among patients who underwent surgery for degenerative cervical myelopathy, most significant neurological improvement occurred by 3 months after surgery. These findings will facilitate valid discussions about postoperative expectations during shared clinical decision making between patients and their surgeons.