Details

Autor(en) / Beteiligte

• Liu, Yan
• Liao, Shou‐Heng
• Dai, Wen‐Tao
• Bai, Qixia
• Lu, Shuai
• Wang, Heng
• Li, Xiaopeng
• Zhang, Zhe
• Wang, Pingshan
• Lu, Wei
• Zhang, Qi

Titel

Controlled Construction of Heteroleptic [Pd2(LA)2(LB)(LC)]4+ Cages: A Facile Approach for Site‐Selective endo‐Functionalization of Supramolecular Cavities

Ist Teil von

• Angewandte Chemie International Edition, 2023-02, Vol.62 (6), p.e202217215-n/a

Auflage

International ed. in English

Ort / Verlag

Germany: Wiley Subscription Services, Inc

Erscheinungsjahr

2023

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Construction of supramolecular structures with internal functionalities is a promising approach to build enzyme‐like cavities. The endo‐functionalized [Pd12L24] and [Pd2L4] coordination cages represent the most successful systems in this regard. However, these systems mainly contain one type of endo‐moiety. We herein provide a solution for the controlled endo‐functionalization of [Pd2L4] cages. Site‐selective introduction of the endo‐functional group was achieved through the formation of heteroleptic [Pd2(LA)2(LB)(LC)] cages. Using two orthogonal steric control elements is the key for the selective formation of the hetero‐assemblies. We demonstrated the construction of two hetero‐cages with a single internal functional group as well as a hetero‐cage with two distinct endohedral functionalities. The endo‐functionalized hetero‐cages bound sulfonate guests with fast‐exchange dynamics. This strategy provides a new solution for the controlled endo‐functionalization of supramolecular cavities. Unprecedented heteroleptic [Pd2 (LA)2 (LB) (LC)] supramolecular cages were selectively constructed by taking advantage of a pair of orthogonal steric control elements encoded in distinct ligands. This strategy allows the site‐selective introduction of distinct endo‐functionalities into the cavity of the heteroleptic cage.