Details

Autor(en) / Beteiligte

• Kampaktsis, Polydoros N.
• Doulamis, Ilias P.
• Vavuranakis, Manolis
• Kuno, Toshiki
• Briasoulis, Alexandros

Titel

Further Reduction in Mortality Rates from Aortic Stenosis in the United States With Ongoing Inequities

Ist Teil von

• The American journal of cardiology, 2023-01, Vol.187, p.162-163

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2023

Quelle

MEDLINE

Beschreibungen/Notizen

• Notably, mortality due to aortic stenosis had remained unchanged in minorities and the nonmetropolitan population, signifying potential inequities in access to advanced cardiac care.1,2 Since 2018, however, the number of TAVR performed in the United States has continued to increase and surpassed the total number of surgical aortic valve replacements.3 In addition, TAVR is now approved by the Food and Drug Administration for patients with low-risk aortic stenosis after the results of the Placement of Aortic Transcatheter Valves (PARTNER) 3 trial, which showed improved outcomes of TAVR compared to surgery.4 We therefore sought to assess the impact of these major changes on recent mortality rates from aortic stenosis in the US. Among patients aged 75 years or older, mortality rates due to aortic stenosis continued to decrease in the study period (APC −1.77, 95% CI −3.25 to −0.27), appearing to plateau between 2018 and 2020. [...]the decision for and timing of intervention in patients with severe aortic stenosis has a crucial role on outcomes and can be influenced by cultural factors of the patients, which were not investigated in the present study.Disclosures The authors have no conflicts of interest to declare.