Details

Autor(en) / Beteiligte

• Grimes, David Robert

Titel

Limitations of the radiosensitivity index as a direct prognostic marker

Ist Teil von

• The lancet oncology, 2022-11, Vol.23 (11), p.1352-1353

Ort / Verlag

London: Elsevier Ltd

Erscheinungsjahr

2022

Quelle

Elsevier ScienceDirect Journals Complete

Beschreibungen/Notizen

• [...]the radiosensitivity index itself must be put in biophysical context for its strengths and limitations to be identified. Because the radiosensitivity index is a ranked linear model, it can only take a finite number of possible values; ten genes can be ranked in 10! (10 factorial) ways, for a total of 3 628 800 potential values. [...]the need remains for more fundamental research on genomic markers that are likely to predict radiotherapy response.