Details

Autor(en) / Beteiligte

• Alemayehu, Tinsae
• Gebeyehu, Netsanet Azene

Titel

Recurrent Infections in an Ethiopian Boy with Autosomal Recessive Major Histocompatibility Complex Type I Deficiency: a Case Report on a Very Rare Primary Immunodeficiency Disorder and a Review of Principles in Evaluation and Management

Ist Teil von

• Journal of clinical immunology, 2023, Vol.43 (1), p.241-243

Ort / Verlag

New York: Springer US

Erscheinungsjahr

2023

Quelle

MEDLINE

Beschreibungen/Notizen

• Little is known about major histocompatibility complex type I deficiency, a rare form of primary immunodeficiency. This report describes the presentation of a three-year-old Ethiopian boy with recurrent sinopulmonary infections and genetic analysis showing him having autosomal recessive major histocompatibility complex type I deficiency—the first such report in a child of black African descent—and follows it with a summary of existing literature on the epidemiology, presentation, and diagnosis as well as principles of management of this disorder.