Details

Autor(en) / Beteiligte

• Li, Qingsi
• Wen, Chiyu
• Yang, Jing
• Zhou, Xianchi
• Zhu, Yingnan
• Zheng, Jie
• Cheng, Gang
• Bai, Jie
• Xu, Tong
• Ji, Jian
• Jiang, Shaoyi
• Zhang, Lei
• Zhang, Peng

Titel

Zwitterionic Biomaterials

Ist Teil von

• Chemical reviews, 2022-12, Vol.122 (23), p.17073-17154

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2022

Quelle

MEDLINE

Beschreibungen/Notizen

• The term “zwitterionic polymers” refers to polymers that bear a pair of oppositely charged groups in their repeating units. When these oppositely charged groups are equally distributed at the molecular level, the molecules exhibit an overall neutral charge with a strong hydration effect via ionic solvation. The strong hydration effect constitutes the foundation of a series of exceptional properties of zwitterionic materials, including resistance to protein adsorption, lubrication at interfaces, promotion of protein stabilities, antifreezing in solutions, etc. As a result, zwitterionic materials have drawn great attention in biomedical and engineering applications in recent years. In this review, we give a comprehensive and panoramic overview of zwitterionic materials, covering the fundamentals of hydration and nonfouling behaviors, different types of zwitterionic surfaces and polymers, and their biomedical applications.