Details

Autor(en) / Beteiligte

• Wang, Wei
• Liu, Jinbao
• Mishra, Bharat
• Mukhtar, M. Shahid
• McDowell, John M.

Titel

Sparking a sulfur war between plants and pathogens

Ist Teil von

• Trends in plant science, 2022-12, Vol.27 (12), p.1253-1265

Ort / Verlag

England: Elsevier Ltd

Erscheinungsjahr

2022

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• The biochemical versatility of sulfur (S) lends itself to myriad roles in plant–pathogen interactions. This review evaluates the current understanding of mechanisms by which pathogens acquire S from their plant hosts and highlights new evidence that plants can limit S availability during the immune responses. We discuss the discovery of host disease-susceptibility genes related to S that can be genetically manipulated to create new crop resistance. Finally, we summarize future research challenges and propose a research agenda that leverages systems biology approaches for a holistic understanding of this important element’s diverse roles in plant disease resistance and susceptibility. Genome analysis has revealed surprising diversity in mechanisms through which pathogens obtain sulfur (S) from their hosts during infection, and transcriptomics has uncovered variation in the modes of S uptake and metabolism during pathogen infection cycles.Functional genomics of pathogen virulence proteins points toward mechanisms through which the pathogen is directly manipulating a plant S transport gene. In turn, this gene has been engineered to resist pathogen manipulation and provide disease resistance.Mounting evidence indicates that plants can interpret S deficiency as a signal of pathogen invasion and can withhold S from pathogens as a component of the immune response. This aspect of ‘competition’ is emerging for other nutrients and represents a major area of growth in our understanding of the interrelated nature of pathogen virulence and plant immunity.