Details

Autor(en) / Beteiligte

• Li, Chenxi
• He, Wen‐Qiang

Titel

Comparison of primary liver cancer mortality estimates from World Health Organization, global burden disease and global cancer observatory

Ist Teil von

• Liver international, 2022-10, Vol.42 (10), p.2299-2316

Ort / Verlag

Hoboken: Wiley Subscription Services, Inc

Erscheinungsjahr

2022

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• Aims This study aims to compare estimates of primary liver cancer mortality from World Health Organization (WHO), Global Burden Disease (GBD) and Global Cancer Observatory (GCO). Methods Liver cancer mortality was extracted from WHO, GBD and GCO for 92 countries for the most recent year. Age‐standardized rate (ASR) was computed and used for current comparisons across the three data sources. Temporal trend for 75 countries was analysed and compared between WHO and GBD from 1990 to 2019 using joinpoint regression. Average annual percentage change for the most recent 10 years was used as indicator for change. Results The estimates of ASR were quite consistent across the three data sources, but most similar estimates were found between WHO and GCO in both region and country levels. The differences in ASR were negatively correlated with completeness of cause‐of‐death registration, human development index and proportion of liver cancer because of alcohol consumption. Consistent trends of ASR were found from 35 countries between WHO and GBD in the most recent 10 years. However, opposite trends were found from 10 countries with five from Southern America, four from Europe and one from Asia. Of the 18 countries for projection, opposite trends between WHO and GBD were found from seven countries. Conclusion While the ASR of primary liver cancer mortality was comparable across the three data sources, most similar estimates were found between WHO and GCO. The opposite trends found from 10 countries between WHO and GBD raised concerns of true patterns in these countries. Lay summary To date, the global estimates of primary liver cancer mortality have been provided by World Health Organization, Global Burden Disease, and Global Cancer Observatory, yet no study has compared the current estimates of primary liver cancer mortality from different data sources globally. This study aims to compare the most recent estimates of primary liver cancer mortality from 92 countries across these three sources. The comparisons were also made through the temporal trend analysis from 1990 to 2019, and the projection to 2030 between WHO and GBD. While the estimates of primary liver cancer mortality were comparable across the three data sources for 92 countries, most similar estimates were found between WHO and GCO. Opposite trends in the most recent 10 years were identified from five Southern American countries (Colombia, Cuba, Dominican Republic, Jamaica and Mexico), four European countries (Latvia, Sweden, Cyprus and Poland) and one Asian country (Uzbekistan).