The New England journal of medicine, 2022-06, Vol.386 (26), p.2471-2481
- Gállego Pérez-Larraya, Jaime
- Garcia-Moure, Marc
- Labiano, Sara
- Patiño-García, Ana
- Dobbs, Jessica
- Gonzalez-Huarriz, Marisol
- Zalacain, Marta
- Marrodan, Lucia
- Martinez-Velez, Naiara
- Puigdelloses, Montserrat
- Laspidea, Virginia
- Astigarraga, Itziar
- Lopez-Ibor, Blanca
- Cruz, Ofelia
- Oscoz Lizarbe, Miren
- Hervas-Stubbs, Sandra
- Alkorta-Aranburu, Gorka
- Tamayo, Ibon
- Tavira, Beatriz
- Hernandez-Alcoceba, Ruben
- Jones, Chris
- Dharmadhikari, Gitanjali
- Ruiz-Moreno, Cristian
- Stunnenberg, Henk
- Hulleman, Esther
- van der Lugt, Jasper
- Idoate, Miguel Á.
- Diez-Valle, Ricardo
- Esparragosa Vázquez, Inés
- Villalba, Maria
- de Andrea, Carlos
- Núñez-Córdoba, Jorge M.
- Ewald, Brett
- Robbins, Joan
- Fueyo, Juan
- Gomez-Manzano, Candelaria
- Lang, Frederick F.
- Tejada, Sonia
- Alonso, Marta M.
2022
Details
- Autor(en) / Beteiligte
- Gállego Pérez-Larraya, Jaime
- Garcia-Moure, Marc
- Labiano, Sara
- Patiño-García, Ana
- Dobbs, Jessica
- Gonzalez-Huarriz, Marisol
- Zalacain, Marta
- Marrodan, Lucia
- Martinez-Velez, Naiara
- Puigdelloses, Montserrat
- Laspidea, Virginia
- Astigarraga, Itziar
- Lopez-Ibor, Blanca
- Cruz, Ofelia
- Oscoz Lizarbe, Miren
- Hervas-Stubbs, Sandra
- Alkorta-Aranburu, Gorka
- Tamayo, Ibon
- Tavira, Beatriz
- Hernandez-Alcoceba, Ruben
- Jones, Chris
- Dharmadhikari, Gitanjali
- Ruiz-Moreno, Cristian
- Stunnenberg, Henk
- Hulleman, Esther
- van der Lugt, Jasper
- Idoate, Miguel Á.
- Diez-Valle, Ricardo
- Esparragosa Vázquez, Inés
- Villalba, Maria
- de Andrea, Carlos
- Núñez-Córdoba, Jorge M.
- Ewald, Brett
- Robbins, Joan
- Fueyo, Juan
- Gomez-Manzano, Candelaria
- Lang, Frederick F.
- Tejada, Sonia
- Alonso, Marta M.
- Titel
- Oncolytic DNX-2401 Virus for Pediatric Diffuse Intrinsic Pontine Glioma
- Ist Teil von
- The New England journal of medicine, 2022-06, Vol.386 (26), p.2471-2481
- Ort / Verlag
- United States: Massachusetts Medical Society
- Erscheinungsjahr
- 2022
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- A total of 12 pediatric patients with diffuse intrinsic pontine glioma were treated with a direct infusion of an oncolytic virus, followed by radiotherapy. The tumor size was reduced in 9 patients, and disease was stable over a median follow-up of 18 months in 8 patients.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793eISSN: 1533-4406DOI: 10.1056/NEJMoa2202028Titel-ID: cdi_proquest_miscellaneous_2682258193
- Format
- –
- Schlagworte
- Adenoviridae, Adolescent, Adverse events, Antitumor activity, Astrocytoma - radiotherapy, Astrocytoma - therapy, Autopsy, Biopsy, Blood tests, Brain cancer, Brain Stem Neoplasms - mortality, Brain Stem Neoplasms - pathology, Brain Stem Neoplasms - radiotherapy, Brain Stem Neoplasms - therapy, Brain Tumor, Brain tumors, Cancer in children, Care and treatment, Cerebellum, Child, Child, Preschool, Childhood Cancer, Childhood Diseases, Diffuse Intrinsic Pontine Glioma - mortality, Diffuse Intrinsic Pontine Glioma - radiotherapy, Diffuse Intrinsic Pontine Glioma - therapy, Glioma, Glioma - radiotherapy, Glioma - therapy, Gliomas, Hematology, Humans, Immune response, Infectious Disease, Infusions, Intralesional, Lymphocytes T, Magnetic resonance imaging, Medical prognosis, Nausea, Neuroimaging, Neurology, Neurosurgery, Oncology, Oncolysis, Oncolytic Virotherapy - adverse effects, Oncolytic Virotherapy - methods, Oncolytic Viruses, Paresis, Patients, Pediatrics, Pediatrics General, Peripheral blood, Quality of Life, Radiation therapy, Treatments in Oncology, Tumor cells, Tumor Microenvironment, Viral Infections, Viruses, Vomiting