Details

Autor(en) / Beteiligte

• Song, Kun‐Baek
• Park, Min Jee
• Choi, Eom Ji
• Jung, Sungsu
• Yoon, Jisun
• Cho, Hyun‐Ju
• Kim, Bong‐Seong
• Ahn, Kangmo
• Kim, Kyung Won
• Shin, Youn Ho
• Suh, Dong In
• Hong, Soo‐Jong
• Lee, So‐Yeon

Titel

Food allergy in early childhood increases the risk of oral allergy syndrome in schoolchildren: A birth cohort study

Ist Teil von

• Pediatric allergy and immunology, 2022-05, Vol.33 (5), p.e13786-n/a

Ort / Verlag

England: Wiley Subscription Services, Inc

Erscheinungsjahr

2022

Quelle

Wiley Blackwell Single Titles

Beschreibungen/Notizen

• Background The level of pollen in Korea has increased over recent decades. Research suggests that oral allergy syndrome (OAS) may be more frequent in childhood than previously recognized. We aimed to investigate the prevalence and characteristics of OAS in children aged 6–10 years from a general‐population‐based birth cohort. Methods We analyzed 930 children from the cohort for childhood origin of asthma and allergic diseases (COCOA). Allergic diseases were diagnosed annually by pediatric allergists. The skin prick tests were performed with 14 common inhalant allergens and four food allergens for the general population of children aged 3 and 7 years. Results Of the 930 eligible children, 44 (4.7%) aged 6–10 years were diagnosed with OAS. The mean age at onset was 6.74 years. OAS prevalence was 7.2% among children with allergic rhinitis (AR) and 19.1% among those with pollinosis, depending on comorbidity. OAS was more prevalent in schoolchildren with atopic dermatitis, food allergy, and sensitization to food allergens and grass pollen in early childhood. In schoolchildren with AR, only a history of food allergy until the age of 3 years increased the risk of OAS (aOR 2.971, 95% CI: 1.159–7.615). Conclusion Food allergy and food sensitization in early childhood were associated with OAS in schoolchildren with AR. Further study is required to elucidate the mechanism by which food allergy in early childhood affects the development of OAS.