Details

Autor(en) / Beteiligte

• Wang, Xin
• Pan, Si-Lin
• DU, Zhan-Hui
• Ji, Zhi-Xian
• Luo, Gang
• Sun, Hong-Xiao
• Ma, Shu-Jing

Titel

Association between duration of fever before treatment and intravenous immunoglobulin resistance in Kawasaki disease

Ist Teil von

• Zhongguo dang dai er ke za zhi, 2022-04, Vol.24 (4), p.399-404

Ort / Verlag

China

Erscheinungsjahr

2022

Quelle

MEDLINE

Beschreibungen/Notizen

• To examine the association between duration of fever before intravenous immunoglobulin (IVIG) treatment and IVIG resistance in children with Kawasaki disease (KD). A retrospective analysis was performed on the medical data of 317 children with KD who were admitted from January 2018 to December 2020. According to the duration of fever before IVIG treatment, they were divided into two groups: short fever duration group (≤4 days) with 92 children and long fever duration group (>4 days) with 225 children. According to the presence or absence of IVIG resistance, each group was further divided into a drug-resistance group and a non-drug-resistance group. Baseline data and laboratory results were compared between groups. A multivariate logistic regression analysis was used to identify the influencing factors for IVIG resistance. In the short fever duration group, 19 children (20.7%) had IVIG resistance and 5 children (5.4%) had coronary artery aneurysm, and in the long fever duration group, 22 children (9.8%) had IV