Details

Autor(en) / Beteiligte

• Kato, Daiki
• Ebara, Shin
• Tatenuma, Tomoyuki
• Sasaki, Takeshi
• Ikehata, Yoshinori
• Nakayama, Akinori
• Toide, Masahiro
• Yoneda, Tatsuaki
• Sakaguchi, Kazushige
• Teishima, Jun
• Makiyama, Kazuhide
• Inoue, Takahiro
• Kitamura, Hiroshi
• Saito, Kazutaka
• Koga, Fumitaka
• Urakami, Shinji
• Koie, Takuya

Titel

Short‐term oncological and surgical outcomes of robot‐assisted radical prostatectomy: A retrospective multicenter cohort study in Japan (the MSUG94 group)

Ist Teil von

• Asian journal of endoscopic surgery, 2022-10, Vol.15 (4), p.745-752

Ort / Verlag

Kyoto, Japan: John Wiley & Sons Australia, Ltd

Erscheinungsjahr

2022

Link zum Volltext

Quelle

Wiley Online Library Journals Frontfile Complete

Beschreibungen/Notizen

• Introduction We evaluated oncological outcomes of patients undergoing robot‐assisted radical prostatectomy (RARP) for prostate cancer (PCa) and their perioperative complications in Japan. We investigated clinical and pathological covariates to predict biochemical recurrence (BCR) after RARP. Methods A retrospective multicenter cohort study was conducted in RARP patients with PCa at 10 institutions in Japan. Pre‐ and postoperative covariates were collected from enrolled patients. The primary endpoint was defined as biochemical recurrence‐free survival (BRFS). Additionally, the association between BCR and clinicopathological covariates was determined. Results We enrolled 2670 patients in this study. The median follow‐up period was 26.0 months. RARP‐related perioperative complications were identified in 198 patients (7.4%), including 69 patients (2.6%) with grade 3/4 complications according to the Clavien–Dindo classification. The 2‐year BRFS was 88.0%. Using the Kaplan–Meier method, initial prostate‐specific antigen (PSA) level of ≤7.6 ng/mL, biopsy and pathological Gleason score (GS) of ≤7, clinical and pathological T1/2, and low/intermediate risks according to the National Comprehensive Cancer Network risk classification, and negative surgical margin status had significant BRFS than their counterparts. In multivariate analysis, initial PSA, biopsy and pathological GS, clinical and pathological T stage, and surgical margin status significantly correlated with BCR after RARP. Conclusion In this study, RARP achieved a lower incidence of perioperative complications than other studies.