Details

Autor(en) / Beteiligte

• Guo, Rui‐Li
• Zhang, Xing‐Long
• Bu, Xian‐Pan
• Wang, Meng‐Yue
• Zhao, Bao‐Yin
• Gao, Ya‐Ru
• Jia, Qiong
• Wang, Yong‐Qiang

Titel

Se‐(Fluoromethyl) Benzenesulfonoselenoates: Shelf‐Stable, Easily Available Reagents for Monofluoromethylselenolation

Ist Teil von

• Chemistry : a European journal, 2022-07, Vol.28 (39), p.e202200981-n/a

Ort / Verlag

Germany: Wiley Subscription Services, Inc

Erscheinungsjahr

2022

Quelle

Wiley Online Library

Beschreibungen/Notizen

• A new class of electrophilic monofluoromethylselenolation reagents, Se‐(fluoromethyl) benzenesulfonoselenoates, has been developed. They can be readily prepared from sodium benzenesulfinates, Se powder and ClCFH2 in one step under mild reaction conditions. Se‐(fluoromethyl) benzenesulfonoselenoates are efficient electrophilic monofluoromethylselenolation reagents for a wide range of nucleophiles including indole, 6‐azaindole, pyrrole, thiophene, electron‐rich arene, aryl boronic acid and alkyne. The monofluoromethylselenolation approach features mild and environmentally friendly reaction conditions, good tolerance of various functional groups, and broad substrate scope. A new class of electrophilic monofluoromethylselenolation reagents, Se‐(fluoromethyl) benzenesulfonoselenoates 2, has been developed, which can be facilely prepared in one step and enable the monofluoromethylselenolation for a wide range of nucleophiles including indole, 6‐azaindole, pyrrole, thiophene, electron‐rich arene, aryl boronic acid and alkyne under mild reaction conditions.