The New England journal of medicine, 2022-04, Vol.386 (17), p.1615-1626
2022
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Details
- Autor(en) / Beteiligte
- Titel
- Prefusion F Protein–Based Respiratory Syncytial Virus Immunization in Pregnancy
- Ist Teil von
- The New England journal of medicine, 2022-04, Vol.386 (17), p.1615-1626
- Ort / Verlag
- United States: Massachusetts Medical Society
- Erscheinungsjahr
- 2022
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Respiratory syncytial virus is a major cause of illness in infants. In this randomized, double-blind, placebo-controlled trial, the safety and immunogenicity of a bivalent RSV prefusion F protein–based vaccine was assessed in pregnant women and their infants. Anti-RSV antibodies were elicited with efficient transplacental transfer.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793eISSN: 1533-4406DOI: 10.1056/NEJMoa2106062Titel-ID: cdi_proquest_miscellaneous_2656743322
- Format
- –
- Schlagworte
- Age, Aluminum hydroxide, Aluminum Hydroxide - adverse effects, Antibodies, Antibodies, Neutralizing - blood, Antibodies, Neutralizing - immunology, Antibodies, Viral - immunology, Babies, Childhood Diseases, Confidence intervals, Congenital diseases, Cord blood, Coronaviruses, COVID-19, F protein, Female, Gynecology, Gynecology General, Health surveillance, Humans, Hypothesis testing, Illnesses, Immunization, Immunogenicity, Infant, Infants, Infections, Infectious Disease, Monoclonal antibodies, Neonatology, Obstetrics, Pandemics, Pediatrics, Placebos, Pregnancy, Proteins, Respiratory diseases, Respiratory syncytial virus, Respiratory Syncytial Virus Infections - immunology, Respiratory Syncytial Virus Infections - prevention & control, Respiratory Syncytial Virus Vaccines - adverse effects, Respiratory Syncytial Virus Vaccines - immunology, Respiratory Syncytial Virus Vaccines - therapeutic use, Respiratory Syncytial Virus, Human - immunology, Safety, Statistical analysis, Vaccination, Vaccines, Viral Fusion Proteins - immunology, Viral Infections, Womens health