Details

Autor(en) / Beteiligte

• Khalil, Nasr Y
• Bakheit, Ahmed H
• Alkahtani, Hamad M
• Al-Muhanna, Turki

Titel

Vinpocetine (A comprehensive profile)

Ist Teil von

• Profiles of drug substances, excipients, and related methodology, 2022, Vol.47, p.1-54

Ort / Verlag

Netherlands

Erscheinungsjahr

2022

Link zum Volltext

Beschreibungen/Notizen

• Vinpocetine (VIN) is a herbal supplement extracted from the periwinkle plant. It is a multi-action agent, which is used to treat various neurological disorders such as Alzheimer's and Parkinson's disease. Vinpocetine has also anti-inflammatory, analgesic, antioxidant property and treats various thinking and memory problems. Currently, vinpocetine is also available in the market as a dietary supplement to enhance cognition and memory. This profile explains the physicochemical properties, methods of preparation, content of related impurities and different spectroscopical behavior of vinpocetine. It also discusses the reported methods of analysis of the drug, which include Compendial Methods, Electrochemical Methods, Spectrophotometric Methods and Chromatographic Methods of analysis. Furthermore, this profile explains the stability of the drug subjected to stress conditions of acid, alkaline and photolytic degradation. In addition, the clinical applications of the drug, its uses, side effects, dosing information, pharmacokinetics and mechanism of action are also discussed.