Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist gegebenenfalls nur via VPN oder Shibboleth (DFN-AAI) möglich. mehr Informationen...
Living donors are healthy individuals who are exposed to a major surgical procedure during which a major part of their liver is resected. Data on the long‐term consequences of living liver donation are scarce. This study examined clinical, laboratory, and long‐term health‐related quality of life (HRQoL) in 237 living liver donors and 239 matched controls during 48–168 months of postdonation follow‐up. We used the 36‐item short‐form health survey (SF‐36), version 1. The scores for the four following subscales were higher in nondonors than in donors: physical functioning (p = 0.009), role limitations due to physical health (p = 0.002), energy/fatigue (p < 0.001), and bodily pain (p < 0.001). The scores on the eight subscales of the SF‐36 were higher in donors with living recipients than in donors whose recipients died (p < 0.001). Our results suggest that living donor right hepatectomy is safe and results in a postdonation HRQoL similar to that of nondonors in those donors whose recipients are healthy, whereas donors whose recipients die have a lower HRQoL that is significantly negatively correlated with the time since recipient death and improves over time.