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Trends of primary glomerular disease in Turkey: TSN-GOLD registry report
Ist Teil von
International urology and nephrology, 2022-09, Vol.54 (9), p.2285-2294
Ort / Verlag
Dordrecht: Springer Netherlands
Erscheinungsjahr
2022
Quelle
Alma/SFX Local Collection
Beschreibungen/Notizen
Background
Although several renal biopsy registry reports have been published worldwide, there are no data on primary glomerular disease trends in Turkey.
Methods
Three thousand eight-hundred fifty-eight native kidney biopsy records were assessed in the Turkish Society of Nephrology Primary Glomerulopathy Working Group (TSN-GOLD) Registry. Secondary disease and transplant biopsies were not recorded in the registry. These records were divided into four periods, before 2009, 2009 to 2013, 2013–2017, and 2017–current.
Results
A total of 3858 patients (43.6% female, 6.8% elderly) were examined. Nephrotic syndrome was the most common biopsy indication in all periods (58.6%, 53%, 44.1%, 51.6%, respectively). In the whole cohort, IgA nephropathy (IgAN) (25.7%) was the most common PGN with male predominance (62.7%), and IgAN frequency steadily increased through the periods (
×
2 = 198,
p
< 0.001). MGN was the most common nephropathy in the elderly (> 65 years), and there was no trend in this age group. An increasing trend was seen in the frequency of overweight patients (
×
2 = 37,
p
< 0.0001). Although the biopsy rate performed with interventional radiology gradually increased, the mean glomeruli count in the samples did not change over the periods.
Conclusions
In Turkey, IgAN is the most common primary glomerulonephritis, and the frequency of this is increasing.