Details

Autor(en) / Beteiligte

• Sun, Ming‐Hui
• Ji, Yu‐Fei
• Li, Guo‐Hui
• Shao, Jian‐Wei
• Chen, Rui‐Xu
• Gong, Huan‐Yu
• Chen, Shou‐Yi
• Chen, Ji‐Ming

Titel

Highly adaptive Phenuiviridae with biomedical importance in multiple fields

Ist Teil von

• Journal of medical virology, 2022-06, Vol.94 (6), p.2388-2401

Ort / Verlag

United States: Wiley Subscription Services, Inc

Erscheinungsjahr

2022

Quelle

Wiley Online Library Journals Frontfile Complete

Beschreibungen/Notizen

• The newly established virus family Phenuiviridae in Bunyavirales harbors viruses infecting three kingdoms of host organisms (animals, plants, and fungi), which is rare in known virus families. Many phenuiviruses are arboviruses and replicate in two distinct hosts (e.g., insects and humans or rice). Multiple phenuivirid species, such as Dabie bandavirus, Rift Valley fever phlebovirus, and Rice stripe tenuivirus, are highly pathogenic to humans, animals, or plants. They impose heavy global burdens on human health, livestock industry, and agriculture and are research hotspots. In recent years the taxonomy of Phenuiviridae has been expanded greatly, and research on phenuiviruses has made significant progress. With these advances, this review drew a novel panorama regarding the biomedical significance, distribution, morphology, genomics, taxonomy, evolution, replication, transmission, pathogenesis, and control of phenuiviruses, to aid researchers in various fields to recognize this highly adaptive and important virus family and conduct relevant risk analysis. Key Points/Highlights 1. This review draws a novel panorama for the virus family Phenuiviridae. 2. Phenuiviridae has importance in the health of humans, animals, and plants. 3. Structures, functions, and evolution of phenuivirid genes were reviewed. 4. Pathogenesis, epidemiology, and control of phenuiviruses were reviewed.